I agree with the previous post: there's a lot of gold packed into Anita's article.

I'd like to bolster two points:

As Anita said, it's better to start with more resolution: "Make it 300 dpi so that text and graphics will be sharp even when downsampled and compressed."

Designers may assume that the reading platform for your eBook will be low resolution screen or some memory constrained device such as the current Palm and PocketPC machines or LCD notebook screens. That could be a mistake given the pace of advances in screen technology. Hopefully, people will still be looking at the book a year or two or three from now.

I also second the considerations for people with older vision. My eyes are going through this change of life and I have problems with many web and print pages. Some things can be resized but it's still a pain.

I apologize, I can't help myself, it's the editor in me...

Your phrase:
"Finally, don't waste undo time on kerning individual letter pairs, ..."

should read: "...don't waste UNDUE time on kerning..."

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This business of e-books is fascinating to me. I want to learn more: how to get involved in development of e-books, business opportunities in design and writing, etc. Your column was great; I'm going to have to invest in InDesign.

Only one hitch I've encountered in exporting to PDF within PageMaker. Perhaps this problem has been corrected in PM 7.x, but in version 6.5, Exporting to PDF on a Windows machine is very unstable; the application very often crashes during that process. (Actually the whole application likes to crap out, quite often, regardless of the action.) Hope that was fixed this new version, because I am leaning toward InDesign and getting away from PM altogether.

Thanks for another informative article Anita! Keep up the good work!